Artifacts are special items unlocked by finding rare green crystal drops from enemies, crates, and other usual sources. By collecting three of these crystals, or by opening an artifact crate, you'll be prompted to chose one of three random artifacts. The benefits of that artifact then persists through the run.
Zion
All items cool down 25% faster and the next item found is heavily upgraded.
Savnt
All self-affecting buffs and debuffs last 40% longer.
Ensiferum
Increase weapon carry amount by 1 and grants two weapon upgrade kits.
Mael
Removes movement speed penalty on firing and grants immunity to slowing effects.
Pure 759
Increases the chances of all powerups appearing by 50%.
Taro
Increases critical damage, critical strike chance, and critical chance cap by 15%.
Kokova
Increases healing by 30% and adds 3 charges for class healing items.
Aeon-FFD
All upcoming item and weapon shops, as well as upgrade stations cost 35% less.
Luka
Upgrades starting weapon damage by 25% and minimum heat by 25.
Cario
Gain one additional Dash charge.
RHETT
Enemy Friendly Fire increased by 75%.
Friendly Friendly Fire set to 20%.
Friendly Friendly Fire set to 20%.
PU-55
Terror level is decreased by 30.
Deal 35% more damage to Elites.
Deal 35% more damage to Elites.
RHYNN
Increases poison, fire, bleeding, and radiation damage and increases the maximum stackable damage by 35%.
KEVV
The first dropped weapon comes in an ULTRA variant.
HOBB-S
Ricochets deal 125% additional damage.
All bullets gain 20% chance to ricochet
All bullets gain 20% chance to ricochet
Trivia
Artifacts are named after members of the community.